What specifies the requirements for data submission to its database in NCDB?

The correct choice is the Call for Data, as it is the official document that outlines the requirements for data submission to the National Cancer Database (NCDB). This document typically specifies the types of data that need to be submitted, the format in which they should be presented, and the deadlines for submissions. It serves as a guideline for cancer registries to ensure they are collecting and reporting data accurately and consistently, which is essential for maintaining the integrity of the NCDB's resources.

The Call for Data is vital for establishing a standardized approach to data collection across various cancer registries, allowing for effective aggregation and analysis of cancer data on a national level. This ensures that the database remains a reliable source for cancer research and epidemiology.

The other options mentioned do not serve the specific purpose of laying out data submission requirements in the same comprehensive way. The Survey Application Record is typically used for collecting specific data points but does not set the overarching submission criteria. The NCDB EDITS Metafile involves edit checks and validation rules for data quality but is not focused on submission requirements. Lastly, a quarterly reporting schedule is related to the timing of data submissions but does not clarify the content or standards for the data being submitted.